"The ventilator's adjustment parameters start with the four major settings: tidal volume, respiratory rate, inspiratory-expiratory ratio, and airway peak pressure (PIP). Further refinements include flow magic, inhalation oxygen concentration, alarm settings, ventilator sensitivity, and Positive End-Expiratory Pressure (PEEP). These parameters must be adjusted continuously based on the patient's weight, respiratory symptoms and causes, variations in blood gas analysis, and other biochemical indicators. If the parameters aren't properly adjusted, inappropriate mechanical ventilation can most easily lead to ventilator-induced injuries, particularly barotrauma."