Botulinum Toxin Reaction Simulator & Explorer
View chemical structures, injection simulation, and patient reaction symptoms.
Search by PDB ID, Name, Organism, or Ligand
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CIA Protein Alpha
PDB ID: 1A1X
CIA Protein Alpha
Number
1
CIA Protein Beta
PDB ID: 2B2Y
CIA Protein Beta
Number
2
CIA Ligand Gamma
PDB ID: 3C3Z
CIA Ligand Gamma
Number
3
CIA Enzyme Delta
PDB ID: 4D4A
CIA Enzyme Delta
Number
4
CIA Complex Epsilon
PDB ID: 5E5B
CIA Complex Epsilon
Number
5
CIA Receptor Zeta
PDB ID: 6F6C
CIA Receptor Zeta
Number
6
CIA Channel Eta
PDB ID: 7G7D
CIA Channel Eta
Number
7
CIA Protein Theta
PDB ID: 8H8E
CIA Protein Theta
Number
8
CIA Enzyme Iota
PDB ID: 9I9F
CIA Enzyme Iota
Number
9
CIA Transporter Kappa
PDB ID: 1J1G
CIA Transporter Kappa
Number
10
CIA Scaffold Lambda
PDB ID: 2K2H
CIA Scaffold Lambda
Number
11
CIA Kinase Mu
PDB ID: 3L3I
CIA Kinase Mu
Number
12
CIA Protease Nu
PDB ID: 4M4J
CIA Protease Nu
Number
13
CIA Polymerase Xi
PDB ID: 5N5K
CIA Polymerase Xi
Number
14
CIA Ribosome Omicron
PDB ID: 6O6L
CIA Ribosome Omicron
Number
15
CIA Chaperone Pi
PDB ID: 7P7M
CIA Chaperone Pi
Number
16
CIA Motor Rho
PDB ID: 8Q8N
CIA Motor Rho
Number
17
CIA Adhesion Sigma
PDB ID: 9R9O
CIA Adhesion Sigma
Number
18
CIA Sensor Tau
PDB ID: 1S1P
CIA Sensor Tau
Number
19
CIA Protein Upsilon
PDB ID: 2T2Q
CIA Protein Upsilon
Number
20
CIA Enzyme Phi
PDB ID: 3U3R
CIA Enzyme Phi
Number
21
CIA Complex Chi
PDB ID: 4V4S
CIA Complex Chi
Number
22
CIA Regulator Psi
PDB ID: 5W5T
CIA Regulator Psi
Number
1
Z
0
Ero
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Third
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Step 8
Z
Ero
Third
At Step 0: No immediate symptoms of paralysis, spasms, or nervous system impairment are indicated.
Patient
All
Combine Toxins
Combined toxin exposure may result in neuromuscular weakness, spasms, and autonomic disturbances.
Generate All Reaction Variants
Ascending Paralysis
Dose: moderate · Rate: rapid · Cofactor: absent
Weakness starts in the lower extremities and progresses upwards, potentially affecting respiratory muscles.
Descending Paralysis
Dose: moderate · Rate: rapid · Cofactor: absent
Weakness starts in the head and neck and progresses downwards, potentially affecting respiratory muscles.
Localized Spasms
Dose: low · Rate: steady · Cofactor: present
Involuntary muscle contractions are confined to a specific area, such as the face or a limb.
Generalized Spasms
Dose: moderate · Rate: rapid · Cofactor: absent
Widespread involuntary muscle contractions affecting multiple muscle groups throughout the body.
Autonomic Instability with Weakness
Dose: high · Rate: rapid · Cofactor: present
Muscle weakness accompanied by fluctuations in heart rate, blood pressure, and sweating.
Selective Muscle Weakness
Dose: low · Rate: slow · Cofactor: absent
Weakness affects specific muscle groups, such as those controlling eye movement or swallowing, while other muscles remain unaffected.
Delayed Paralysis
Dose: moderate · Rate: slow · Cofactor: present
Paralysis develops gradually over several hours or days after exposure.
Transient Weakness
Dose: low · Rate: rapid · Cofactor: absent
Brief episodes of muscle weakness that resolve spontaneously.
Atypical/Unknown: Paradoxical Excitation
Dose: low · Rate: steady · Cofactor: present
Instead of weakness, experience increased muscle tone and hyperreflexia.
Atypical/Unknown: Sensory-Motor Dissociation
Dose: moderate · Rate: rapid · Cofactor: absent
Preserved sensory function despite significant motor impairment.
Atypical/Unknown: Fluctuating Symptoms
Dose: moderate · Rate: steady · Cofactor: present
Neuromuscular symptoms wax and wane unpredictably over time.
Atypical/Unknown: Central Apnea
Dose: high · Rate: rapid · Cofactor: absent
Cessation of breathing due to failure of the brain's respiratory control center, without significant muscle weakness.
Mix All Toxins Now
Widespread and unpredictable neuromuscular paralysis, autonomic dysregulation including cardiac arrhythmia and respiratory failure, and likely rapid multi-organ system collapse.
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CIA Enzyme Delta
CIA Enzyme Delta
Function/Use: Metabolic control
Requested quantity: 2 mg
PDB ID 4D4A
Method X-Ray Diffraction
Resolution (Å) 1.9
Organisms Homo sapiens
Macromolecules Enzyme
Ligands HEM
Release Date 2017-03-11